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A new gene has been found that weakens the protein tomosyn-2, resulting in blocking the transfer of insulin in the pancreases resulting in occurrence of diabetes. The finding is being observed as the partial answer to the difference in the susceptibility rate towards diabetes among people.
The researchers from the University of Wisconsin-Madison came across the protein tomosyn-2 and its biology during their search for genes responsible for varied vulnerability towards the disease of diabetes. The research was carried out on genetically engineered mice that were compared for their deadness against diabetes and their vulnerability towards it.
It is during the analysis; the researchers found that a minor difference in the level of amino acid resulted in weakening the tomosyn-2 protein among the mice that are dead against diabetes, which opened ways for insulin to pass into the pancreas, thereby protecting the mice from diabetes.
According to lead researcher Alan Attie, the discovery so far has revealed about the reaction of gene on mice, but the reaction in human body is yet to be observed. Also, the co-author of the research, Sushant Bhatnagar states, "This study shows the power of genetics to discover new mechanisms for a complex disease like type 2 diabetes".